How to Prepare and Ship Non-Standard DNA Samples for Testing
DNA testing doesn’t always rely on traditional cheek swabs. When standard collection methods aren’t an option, non-standard (forensic) DNA samples—such as hair, toothbrushes, or clothing—can be used to extract genetic material. However, proper handling, storage, and shipping are crucial to preserving the integrity of the DNA for accurate results. This guide outlines best practices for collecting, packaging, and shipping forensic DNA samples for testing.
What Are Non-Standard DNA Samples?
Non-standard, or forensic DNA samples, refer to biological materials that contain DNA but are collected from personal items rather than direct cheek swabs. These samples are useful when an individual is unavailable or unwilling to provide a standard DNA sample.
Common non-standard DNA samples include:
Hair with Root Attached
Used Toothbrushes
Chewed Gum
Cigarette Butts
Nail Clippings
Used Tissues or Condoms
Clothing or Bedding with Bodily Fluids
While these samples can often yield viable DNA, their success rate depends on proper collection and storage.
Best Practices for Collecting Non-Standard DNA Samples
To improve the likelihood of obtaining a successful DNA profile, follow these guidelines:
Minimize Handling – Wear gloves or use tweezers to prevent contamination.
Choose Recently Used Items – The fresher the sample, the higher the likelihood of retrieving viable DNA.
Air Dry Before Packaging – If the sample is damp (e.g., used tissues, clothing), allow it to dry completely to prevent bacterial growth.
Use Paper Envelopes – Avoid plastic bags, as they trap moisture and degrade DNA.
Label Each Sample Clearly – Include the source, date of collection, and any relevant details.
How to Package Non-Standard DNA Samples for Testing
Proper packaging is essential to prevent contamination and DNA degradation. Follow these steps:
Use Separate Envelopes – Place each DNA sample in an individual paper envelope to prevent cross-contamination.
Avoid Plastic Bags – Plastic traps moisture, which can lead to bacterial growth and DNA breakdown.
Seal Securely – Once the sample is inside a paper envelope, seal it properly to keep it intact.
Use a Padded Envelope or Box – For fragile items (like cigarette butts or hair samples), a padded mailer or box provides additional protection.
How to Ship Forensic DNA Samples to the Lab
To ensure the sample arrives in optimal condition, follow these shipping guidelines:
Use a Reliable Carrier – Ship via USPS, FedEx, or UPS with a trackable service.
Avoid Extreme Temperatures – Store and ship samples in a cool, dry place to preserve DNA integrity.
Notify the Lab of Special Samples – If submitting forensic samples, inform the lab for proper handling and processing.
Ship As Soon As Possible – The sooner a sample is tested, the better the chance of retrieving viable DNA.
How Long Do Non-Standard DNA Samples Last?
DNA stability varies depending on the type of sample and storage conditions:
Hair with Root Attached: DNA can last years if stored properly.
Toothbrushes & Chewed Gum: DNA remains viable for months or more but degrades over time.
Used Tissues & Condoms: DNA can last days to weeks, depending on exposure to moisture and bacteria.
Clothing & Fabric Stains: DNA may be detectable for months or years under dry storage conditions.
For best results, collect and ship samples as soon as possible after collection.
When to Use Non-Standard DNA Samples
Non-standard DNA samples are ideal in cases where a cheek swab isn’t possible, such as:
Infidelity DNA Testing – Testing for the presence of foreign DNA or bodily fluids.
Paternity & Relationship DNA Testing – When the alleged father or family member is unavailable for direct testing.
Forensic & Investigative Testing – DNA retrieval for personal, private, or legal investigations.
While buccal swabs are the gold standard, forensic DNA extraction makes it possible to analyze DNA from alternative sources.
Ensuring Accurate Results with Forensic DNA Testing
Using non-standard DNA samples for testing requires careful handling, storage, and shipping to preserve the sample’s integrity. Following best practices can significantly improve the likelihood of a conclusive DNA profile.
At Validity Genetics, we provide expert forensic DNA testing for cases requiring special samples. Contact us today to discuss your testing needs and ensure the best possible results.
